If you don't have super expensive sps try using fritz expel-p. Treatment dose is bio filter, coral, invert and plant safe. I use it for treating external parasites on freshwater shrimp but used it on my clown too. (They bring all kinds of nasties from breeders). It is mostly for external parasites and great for worms and does kill some internal too but the main benefit is it acts as an immuno booster so it helps greatly especially if feeding garlic food or adding garlic guard. I have also used it as an immuno booster on fish with ich and it helped alot. Regular dose is safe for everything and triple dose is some of the best coral dip you can buy, literally paralizes flatworms and nudibranches instantly so it's good to have around. Leathers and softies will get upset a couple days but doesn't harm them. Never tried with sps so can't say yet but great for dips.