I have been for years, saves me a ton of money
I recharge Cation, Anion and mixed bed. I use my brine shrimp hatcher to recharge mixed bed, I buy my lye at home hardware and my acid at the pool store.
Basic safety procedures are safety glasses, rubber gloves and always add acid to water, I fill my plastic laundry tub with cold water and put my lye mixing container filled with RODI water in the cold water when I add the lye to the RODI water as it gets really hot and could melt through a plastic container, I add the lye put on the lid and swish it around in the cold water to mix.
I use 350ml RODI and 100ml lye to regenerate 750ml DI resin (one cartridge)